SEROQUEL (quetiapine fumarate) – an atypical antipsychotic agent commonly used to treat schizophrenia and certain types of bipolar disorder. Though the exact mechanism of action of quetiapine is unknown, it is thought that Seroquel exerts its effects in schizophrenia and bipolar depression and mania through a combination of dopamine type 2 (D2) and serotonin type […]
VYVANSE (lisdexamfetamine dimesylate) – a central nervous system (CNS) stimulant commonly used to treat symptoms of attention deficit hyperactivity disorder (ADHD). Amphetamines block the reuptake of norepinephrine and dopamine into the presynaptic neuron and increase the release of these monoamines into the extraneuronal space. The precise mechanism of action of how amphetamines and other CNS […]
SUBOXONE (buprenorphine and naloxone) – a sublingual tablet containing buprenorphine and naloxone commonly used to treat opiate dependence. Buprenorphine is a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor. Naloxone is a potent antagonist at mu-opioid receptors and produces opioid withdrawal signs and symptoms in individuals physically dependent on full […]
NAMENDA (memantine) – an orally active NMDA receptor antagonist commonly used to treat Alzheimer’s disease. Persistent activation of central nervous system N-methyl-D-aspartate (NMDA) receptors by the excitatory amino acid glutamate has been hypothesized to contribute to the symptomatology of Alzheimer’s disease. Memantine is postulated to exert its therapeutic effect through its action as a low […]