NAMENDA (memantine) – an orally active NMDA receptor antagonist commonly used to treat Alzheimer’s disease. Persistent activation of central nervous system N-methyl-D-aspartate (NMDA) receptors by the excitatory amino acid glutamate has been hypothesized to contribute to the symptomatology of Alzheimer’s disease. Memantine is postulated to exert its therapeutic effect through its action as a low […]
HERCEPTIN (trastuzumab) – an HER2/neu receptor antagonist commonly used to treat certain cancers. The HER2 (or c-erbB2) proto-oncogene encodes a transmembrane receptor protein of 185 kDa, which is structurally related to the epidermal growth factor receptor. Herceptin has been shown, in both in vitro assays and in animals, to inhibit the proliferation of human tumor […]
TRUVADA (emtricitabine/tenofovir disoproxil fumarate) – a combination of 2 nucleoside analog HIV-1 reverse transcriptase inhibitors commonly used to treat infection by the human immunodeficiency virus (HIV). FDA approved uses: Truvada is indicated for use in combination with other antiretroviral agents to treat adult and pediatric (age 12 years or older) infections with the HIV-1 virus. […]
GLEEVEC (imatinib mesylate) – a kinase inhibitor drug commonly used to treat certain types of leukemia, myeloproliferative diseases, and certain other malignancies. FDA approved uses: Gleevec is indicated for: Newly diagnosed adult and pediatric patients with Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML) in chronic phase; Patients with Philadelphia chromosome positive chronic myeloid leukemia […]