NIASPAN (niacin extended-release) – a controlled release niacin product commonly used to treat lipid disorders and certain types of cardiovascular disease. The mechanism by which niacin extended-release influences serum lipid profiles has not been well defined. It may involve several actions including partial inhibition of release of free fatty acids from adipose tissue, and increased […]
TOPROL-XL (metoprolol succinate) – a beta-1-selective adrenoreceptor blocking agent commonly used to treat hypertension, angina, and heart failure. The mechanism of the antihypertensive effects of beta-blocking agents has not been elucidated. However, several possible mechanisms have been proposed: (1) competitive antagonism of catecholamines at peripheral (especially cardiac) adrenergic neuron sites, leading to decreased cardiac output; […]
We’ve all heard of the Mediterranean diet, which is a diet rich in olive oil, nuts, beans, fish, fruits, vegetables, and even the occasional glass of wine with dinner. Now, a new study published on the website of the New England Journal of Medicine announced findings that show a definite clinical benefit to the Mediterranean […]
On January 29, 2012 the U.S. Food and Drug Administration approved Kynamro (mipomersen sodium) injection as an addition to lipid-lowering medications and diet to treat patients with a rare type of high cholesterol called homozygous familial hypercholesterolemia (HoFH). The addition of Kynamro helps to reduce low-density lipoprotein-cholesterol (LDL-C), apolipoprotein B, total cholesterol, and non-high density […]