On February 20, 2013 the United States Food and Drug Administration announced an update to its prior warnings about using codeine in children who have undergone surgery for tonsillectomy and/or adenoidectomy. Specifically, the FDA issued a drug safety communication, advising patients that it would require pharmaceutical manufacturers of codeine-containing products to add a black-box warning […]
LIDODERM (lidocaine patch 5%) – topical patch formulation of lidocaine commonly used to treat neuropathic pain. Lidocaine is an amide-type local anesthetic agent and is suggested to stabilize neuronal membranes by inhibiting the ionic fluxes required for the initiation and conduction of impulses. The penetration of lidocaine into intact skin after application of LIDODERM is […]
LYRICA (pregabalin) – a gabanergic antiepileptic drug commonly used to treat various neuropathic pain disorders. LYRICA (pregabalin) binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues. Although the mechanism of action of pregabalin has not been fully elucidated, research with compounds structurally related to […]
OXYCONTIN (oxycodone) – an opioid agonist product commonly used to treat moderate to severe pain in patients requiring continuous around the clock opioid analgesia. FDA approved uses: Oxycontin is indicated for the management of moderate to severe pain when a continuous, around-the-clock opioid analgesic is needed for an extended period of time. OxyContin is NOT […]