REMICADE (infliximab) – a biologic anti-inflammatory agent that binds specifically to TNF-alpha and blocks its interaction with the p75 cell surface TNF receptor. TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. Elevated levels of TNF are found in the synovial fluid of patients with RA, JIA, PsA, and […]
ENBREL (etanercept) – a biologic anti-inflammatory agent that binds specifically to TNF-alpha and blocks its interaction with the p75 cell surface TNF receptor. TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. Elevated levels of TNF are found in the synovial fluid of patients with RA, JIA, PsA, and […]
ADVAIR (fluticasone/salmererol) – an inhaled combination product containing a corticosteroid (fluticasone), and a long-acting beta-2 adrenergic agonist (salmeterol) commonly used to treat asthma and chronic obstructive pulmonary disease (COPD). The mechanism of action for fluticasone/salmererol is related to the two active ingredients. Fluticasone is a potent corticosteroid that posses anti-inflammatory properties, relieving inflammation in the […]
HUMIRA (adalimumab) – a monoclonal antibody that binds specifically to TNF-alpha and blocks its interaction with the p55 and p75 cell surface TNF receptors. Adalimumab also lyses surface TNF expressing cells in vitro in the presence of complement. TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. Elevated levels […]