EPOGEN (epoetin alfa) – an erythropoiesis-stimulating agent (ESA)commonly used to treat anemia due to various conditions. Epogen stimulate erythropoiesis through the same mechanism as endogenous (naturally occurring) erythropoietin. FDA approved uses: Epogen is indicated for the treatment of anemia due to: Chronic Kidney Disease (CKD) in patients on dialysis and not on dialysis. Zidovudine in […]
CELEBREX (celecoxib) – a nonsteroidal anti-inflammatory drug (NSAID) commonly used to treat various arthritic conditions and other types or pain. The mechanism of action of CELEBREX is believed to be due to inhibition of prostaglandin synthesis, primarily via inhibition of cyclooxygenase-2 (COX-2), and at therapeutic concentrations in humans, CELEBREX does not inhibit the cyclooxygenase-1 (COX-1) […]
LYRICA (pregabalin) – a gabanergic antiepileptic drug commonly used to treat various neuropathic pain disorders. LYRICA (pregabalin) binds with high affinity to the alpha2-delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues. Although the mechanism of action of pregabalin has not been fully elucidated, research with compounds structurally related to […]
AVASTIN (bevacizumab) – a vascular endothelial growth factor-specific angiogenesis inhibitor commonly used to treat certain cancers. Bevacizumab binds VEGF and prevents the interaction of VEGF to its receptors (Flt-1 and KDR) on the surface of endothelial cells. The interaction of VEGF with its receptors leads to endothelial cell proliferation and new blood vessel formation in […]