Toprol-XL (metoprolol succinate)

TOPROL-XL (metoprolol succinate) – a beta-1-selective adrenoreceptor blocking agent commonly used to treat hypertension, angina, and heart failure. The mechanism of the antihypertensive effects of beta-blocking agents has not been elucidated. However, several possible mechanisms have been proposed: (1) competitive antagonism of catecholamines at peripheral (especially cardiac) adrenergic neuron sites, leading to decreased cardiac output; […]