SINGULAIR (montelukast) – a leukotriene receptor antagonist commonly used to treat asthma, bronchoconstriction and certain allergic conditions. Leukotrienes have been correlated with the pathophysiology of asthma and allergic rhinitis. Montelukast inhibits physiologic actions of leukotrienes on airways, bronchial smooth muscle, and cells associated with the inflammatory process in asthma or the allergic process in allergic […]
DIOVAN (valsartan) – an angiotensin II receptor antagonist (ARB)commonly used to treat hypertension or heart failure. Angiotensin II is the principal pressor agent of the renin-angiotensin system, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium. Diovan (valsartan) blocks the vasoconstrictor and aldosterone-secreting effects of […]
EPOGEN (epoetin alfa) – an erythropoiesis-stimulating agent (ESA)commonly used to treat anemia due to various conditions. Epogen stimulate erythropoiesis through the same mechanism as endogenous (naturally occurring) erythropoietin. FDA approved uses: Epogen is indicated for the treatment of anemia due to: Chronic Kidney Disease (CKD) in patients on dialysis and not on dialysis. Zidovudine in […]
CELEBREX (celecoxib) – a nonsteroidal anti-inflammatory drug (NSAID) commonly used to treat various arthritic conditions and other types or pain. The mechanism of action of CELEBREX is believed to be due to inhibition of prostaglandin synthesis, primarily via inhibition of cyclooxygenase-2 (COX-2), and at therapeutic concentrations in humans, CELEBREX does not inhibit the cyclooxygenase-1 (COX-1) […]