SEROQUEL (quetiapine fumarate) – an atypical antipsychotic agent commonly used to treat schizophrenia and certain types of bipolar disorder. Though the exact mechanism of action of quetiapine is unknown, it is thought that Seroquel exerts its effects in schizophrenia and bipolar depression and mania through a combination of dopamine type 2 (D2) and serotonin type […]
INCIVEK (telaprevir) – a hepatitis C virus (HCV) NS3/4A protease inhibitor commonly used, in combination with peginterferon alfa and ribavirin, to treat type hepatitis C. Telaprevir exerts its effects by acting directly against the hepatitis C virus. FDA approved uses: Incivek is indicated, in combination with peginterferon alfa and ribavirin, for the treatment of genotype […]
NOVOLOG (insulin aspart recombinant) – an insulin analog indicated to improve glycemic control in adults and children with diabetes mellitus. The primary activity of insulin, including insulin aspart, is regulation of glucose metabolism. Insulin and its analogs blood glucose by facilitating the cellular uptake of glucose and simultaneously inhibiting the output of glucose from the […]
LOVAZA (omega-3-acid ethyl esters) – a combination of ethyl esters of omega 3 fatty acids, principally EPA and DHA commonly used to elevated triglyceride (TG) levels. The mechanism of action of Lovaza is not completely understood. Potential mechanisms of action include inhibition of acyl-CoA:1,2-diacylglycerol acyltransferase, increased mitochondrial and peroxisomal beta-oxidation in the liver, decreased lipogenesis […]