NOVOLOG (insulin aspart recombinant) – an insulin analog indicated to improve glycemic control in adults and children with diabetes mellitus. The primary activity of insulin, including insulin aspart, is regulation of glucose metabolism. Insulin and its analogs blood glucose by facilitating the cellular uptake of glucose and simultaneously inhibiting the output of glucose from the […]
LOVAZA (omega-3-acid ethyl esters) – a combination of ethyl esters of omega 3 fatty acids, principally EPA and DHA commonly used to elevated triglyceride (TG) levels. The mechanism of action of Lovaza is not completely understood. Potential mechanisms of action include inhibition of acyl-CoA:1,2-diacylglycerol acyltransferase, increased mitochondrial and peroxisomal beta-oxidation in the liver, decreased lipogenesis […]
ACTOS (pioglitazone) – a thiazolidinedione (TZD) and an agonist for peroxisome proliferator activated receptor (PPAR) gamma commonly used to treat type 2 diabetes mellitus. ACTOS decreases insulin resistance in the periphery and in the liver resulting in increased insulin-dependent glucose disposal and decreased hepatic glucose output. Pioglitazone is not an insulin secretagogue. FDA approved uses: […]
SYMBICORT (budesonide and formoterol fumarate dihydrate inhalation) – a metered dose beta agonist-corticosteroid inhaler commonly used to treat asthma or chronic obstructive pulmonary disease . Inflammation is an important component in the development of COPD and asthma. Budesonide is a compound of the corticosteroid classes, members of which possess a wide range of inhibitory activities […]